Only a victory will do for Manchester City when they host the Russian side CSKA Moscow on Wednesday evening.
CSKA Moscow rallied from 2-0 down to earn an impressive draw with City in the recent meeting between the two.
The draw has left City with serious work to do to reach the knock out rounds of the competition, with Manuel Pellegrini’s men yet to win.
Manchester City edged out their biggest rivals Manchester United going into the game, with Sergio Aguero scoring the winner.
United were reduced to 10 men in the first period, however it wasn’t easy for the Premier League champions.
CSKA Moscow fell seven points adrift at the top of the Russian league, after they lost 1-0 at home to the league leaders Zenit St. Petersburg.
Javi Garcia scored the game’s only goal, as Andre Villas-Boas’s side moved further clear in their pursuit of the title.
Elsewhere in the group, Bayern will qualify as winners if they beat Roma in the Munich.
The pair met in last season’s competition, with Manchester City winning both games, including a 5-2 win at the Etihad.
David Silva is out through injury, meaning the returning Samir Nasri will feature from a wide position.
City look set to name two forwards again, with both Edin Dzeko and Aguero featuring for the Blues.
Eliaquim Mangala missed the Manchester derby through injury, meaning Martin Demichelis will continue.
Seydou Doumbia started on the bench a fornight ago, however his impact off the bench changed the game.
He will feature on Wednesday evening, along with the Berezutski brothers in a 5-3-2 formation.
The former Manchester United midfielder Zoran Tosic will start for CSKA and will look to make an impact against a previous rival.
Man City: Hart; Clichy, Kompany, Demichelis, Zabaleta; Fernando, Toure, Nasri, Milner; Dzeko, Aguero
CSKA: Akinfeev; V Berezutski, Ignashevich, A Berezutski, Schennikov, Fernandes; Eremenko, Natcho, Tosic; Musa, Doumbia