The Gunners need just a point to ensure that they advance to the last 16 from Group F.
After impressing many people so far in Europe, Arsenal will look to finish the job on Wednesday night knowing that they will need just a point in Naples to advance to the next stage of the competition.
Despite the one loss to Borussia Dortmund, The Gunners have been in scintillating form in the group winning all their other games which has put them three points clear at the top of Group F.
With one eye on Saturday’s game against Manchester City, Arsene Wenger is unlikely to risk anyone with injury concerns meaning that Jack Wilshere is likely to be rested after picking up an ankle knock in Sunday’s 1-1 draw against Everton.
On top of that, Wenger is likely to rotate several players around to maintain the squad’s high fitness levels with the likes of Tomas Rosicky, Carl Jenkinson and Nacho Monreal all likely to start in Italy.
Wenger should be careful not to take the game too lightly though as opponents Napoli will be on full attack knowing that a 3-goal win could see them qualify at Arsenal’s expense.
The Italian side will have it all to do at home though and they will be without the services of captain Marek Hamsik who is injured for the tie alongside full-back Camilo Zuniga.
Arsneal’s summer target Gonzalo Higuain will once again look to show that he made the right decision choosing Napoli over Arsenal whilst Goran Pandev and Jose Callejon will also be out to upset The Gunners on Wednesday night.
The other group game will see Olymique Marseille host Borussia Dortmund with the visitors needing to match or better Napoli’s result to make it through to the last 16.
Dortmund are currently level on points with Napoli but their superior goal difference means that if they match the Italians’ result against Arsenal, they will qualify at the expense of the losing side in Italy.
Jurgen Klopp’s side will be out both Nuri Sahin and Sven Bender for the tie after both players rejoined the injury list after picking up knocks in the 0-1 loss to Bayer Leverkusen in the Bundesliga on Saturday.
Marseille having nothing left to play for in the group and L’OM chances of finishing on a high will be undermined by the loss of Nicolas N;Koulou and Alexis Romao through suspension and Andre Ayew and Mathieu Valbuena to injuries.
Although the Group F qualification battle might seem complicated, Arsenal know that they have the simple task of avoiding defeat to ensure that they qualify for the last 16 and emerge victorious from this year’s Group of Death.