Its another busy night from Group F as punters and fans can watch all the action from Portugal Luxembourg live streaming online with Bet365, as the firm report they are televising the match through their website (KO 18:00GMT).
Portugal’s only shot of making it through automatically is if they can at least beat Luxembourg by six goals and that Russia lose in Baku.
Paulo Bento’s side will still be without many of their top attacking players but with Nani and Cristiano Ronaldo available, anything can be possible for them.
Northern Ireland are 6/1 underdogs to upset Israel as they look to avoiding finish last in a group where Russia are all but certain to seal their World Cup spot with a point against Azerbaijan.
After a disastrous qualifying campaign, Northern Ireland will be keen to get one last win to see them avoid finishing rock bottom of Group F.
Northern Ireland are currently joint bottom with Luxembourg having notched up just 6 points from 9 games so far.
The problem for Michael O’Neill’s side is a lack of goals with Steven Davis and Gareth McAuley leading the way with just 4 goals in their entire international careers.
It means that it could give some of the younger strikers a chance to step up and show themselves as a replacement for David Healy with Aberdeen striker Josh Magennis and Brentford striker Will Grigg likely candidates to start in Tel Aviv.
Israel saw their World Cup hopes ended on Friday as they could only pick up a 1-1 draw with Portugal on Friday afternoon.
The Israeli squad is likely to remain unchanged as to the one that drew with Portugal with goalscorer Eden Ben Bassat a real danger having scored 6 goals in his first 10 international appearances for his side.
But all the attention will switch to Baku where Russia are virtually guaranteed to secure their World Cup spot in their game against Azerbaijan.
Even though the squad is without more well known figures such as Alan Dzagoev and Alex Anyukov, there are still plenty of well known faces that can cause problems such as Alexander Kerzakhov and Yuri Zhirkov.
Azerbaijan will not be likely to pose much of a threat to the Russians however the defending quality of Ali Gokdemir and Ruslan Abigov will make it difficult for the away side to get many goals.
With a lot at stake on Tuesday’s game, a lot of pride will be on the line as everyone looks to give one last push in the final rounds of World Cup qualifying.