Latest Schalke v Chelsea odds, match preview and betting from the Champions League tie in Germany tonight.
Chelsea can secure their place in the knock out rounds of the Champions League when they travel to Schalke.
The pair are the top two in their group, although the Blues hold a three point advantage at the top.
Roberto Di Matteo took over at Schalke and will face his former employers since he was sacked as manager of Chelsea in 2012.
Schalke were beaten 3-2 away to Sporting Lisbon in their last group game, when a point would have given them a real buffer over the Portuguese side.
The former Manchester United midfielder Nani was among the scorers for Sporting, who kept their qualification hopes alive.
Chelsea thrashed Maribor 6-0 at Stamford Bridge, however were held to a draw in Slovenia.
Nemanja Matic’s close range goal earned Chelsea a draw, although Eden Hazard’s missed penalty cost the Blues all three points.
Earlier in the group stage, Klaas-Jan Huntelaar’s goal earned Schalke a 1-1 draw away to Chelsea.
It was Schalke’s first goal in five games against Chelsea, with the Blues unbeaten having won three and drawn two against Tuesday’s opponents.
Julian Draxler is injured for Schalke, meaning Eric Maxim Choupo-Moting, who scored the winner at home to Sporting will start.
Huntelaar scored Schalke’s leveller in the opposite fixture and will lead the line, with Kevin Prince Boateng offering support from midfield.
Diego Costa has previously been rested in the competition and will battle it out with the fit again Loic Remy to lead the line.
Petr Cech is another who has started most games in the tournament and could start ahead of Thiabut Courtois.
Jose Mourinho may rotate his squad slightly, meaning Felipe Luis and Andre Schurrle could start.
FC Schalke: Fahrmann; Uchida, Howedes, Nuestadter, Fuchs; Aogo, Obasi, Boateng, Hoger; Chupo-Moting; Huntelaar
Chelsea: Cech; Azpilicueta, Ivanvoic, Terry, Luis; Matic, Fabregas; Schurrle, Hazard, Oscar; Remy